myPATHOGEN
Infectious disease target discovery - AI-guided pathogen antigen selection
myPATHOGEN is a dedicated computational workflow for infectious disease antigen discovery. It combines sequence-conservation analysis with neoMS presentation prediction, neoIM immunogenicity prediction, and population-coverage optimization. The workflow prioritizes CD4+ and CD8+ T-cell targets that remain conserved across viral, bacterial, and parasitic strains.
What myPATHOGEN delivers
The end-to-end myPATHOGEN workflow has a turnaround time of eight weeks:
- Genome-wide association studies → linking pathogen genetic variation to phenotypes such as virulence, drug resistance, or immune evasion
- Conservation analysis: prioritization of immunogenic epitopes within conserved regions
- Presentation prediction: identification of surface-presented epitopes in populations infected with different strains
- Immunogenicity prediction: identification of presented epitopes recognized by immune cells
- myCONSTRUCT: next-generation string-of-beads design (optional)
- myRNA: next-generation codon optimization (optional)
What is myPATHOGEN?
myPATHOGEN is a dedicated computational workflow for infectious disease antigen discovery. It combines sequence-conservation analysis with neoMS presentation prediction, neoIM immunogenicity prediction, and population-coverage optimization. The workflow prioritizes CD4+ and CD8+ T-cell targets that remain conserved across viral, bacterial, and parasitic strains.
What is the turnaround time for myPATHOGEN?
The end-to-end myPATHOGEN workflow has a turnaround time of eight weeks. Required data and deliverables are confirmed for each project.
Can myPATHOGEN feed into construct design?
Yes. Selected myPATHOGEN targets can proceed to myCONSTRUCT for multi-epitope construct design and myRNA for codon optimization.