myNEO
Personalized neoantigen target discovery — ImmunoEngine for personalized immunotherapies
Our ImmunoEngine for personalized pipeline is IVD-ready, involves whole genome target discovery, and is best-in-class in target prioritization. It fits personalized clinical manufacturing timelines of vaccine and T-cell therapeutics, delivering results from whole genome sequencing to neoantigen selection and product design in one week.
What myNEO delivers
We offer an end-to-end workflow with a turnaround of 5 business days:
- Variant expression analysis
- Translation analysis
- Presentation prediction: identification of MHC-presented epitopes on both MHC-I and MHC-II molecules
- Immunogenicity prediction: identification of presented epitopes recognized by both CD4 and CD8 immune cells
- Final epitope selection: based on antigen score, clonality, functional relevance, and immune-escape likelihood
- Data visualization: web-based, comprehensive solution for navigating complex datasets
- myCONSTRUCT: next-generation string-of-beads design (optional)
- myRNA: next-generation codon optimization (optional)
Transform raw data into actionable insights
To support interpretation of results from ImmunoEngine for personalized, the complex tumor and immune sequencing data is presented in a web-based platform neoHUB specifically designed to provide a comprehensive and intuitive overview of the full patient dataset. The platform empowers clinicians and clinical researchers to efficiently navigate the complexities of cancer genomics, variant analysis, and neoantigen identification and selection.
Frequently asked questions about myNEO
What is the myNEO personalized pipeline?
The myNEO personalized pipeline is an IVD-ready ImmunoEngine workflow for whole genome neoantigen discovery and prioritization, delivering results from sequencing to product design in about one week.
What is neoHUB?
neoHUB is the web-based visualization platform for myNEO personalized results. It helps clinicians and researchers navigate tumor and immune sequencing data, variant analysis, and neoantigen selection.
What is the turnaround time for myNEO personalized discovery?
The end-to-end myNEO personalized workflow has a turnaround of 5 business days.
Can myNEO be combined with construct and codon optimization?
Yes. Optional next steps include myCONSTRUCT for string-of-beads design and myRNA for codon optimization.
Ready to use myNEO?
Talk to our team about integrating myNEO into your discovery or development workflow.